Spravato® (Esketamine) Treatment for Depression

Find Hope with Spravato®

If you’ve tried multiple antidepressants without relief, Spravato® (esketamine) may offer new hope. This FDA-approved nasal spray works differently from traditional antidepressants and is administered safely in our office under medical supervision. Many patients begin noticing improvement within days.

  • Personalized care.
  • Monitored in a calm, private setting.
  • Designed for adults with treatment-resistant depression or suicidal thoughts.
  • Take the next step toward feeling better.

A New Option for Treatment-Resistant Depression

If you’ve tried multiple antidepressants without relief, you’re not alone — and there’s hope. Spravato® (esketamine) is an FDA-approved medication for adults with treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts or behaviors.

Spravato® works differently than traditional antidepressants and may begin to improve symptoms within days for some patients.


How Spravato® Works

Spravato® targets the brain’s glutamate system, which helps regulate mood and emotional connections. By promoting new neural connections, it can help restore brain function and improve mood, thinking, and motivation — especially for those who haven’t responded to standard antidepressants.


What to Expect During Treatment

  • Administration: Spravato® is a nasal spray that you self-administer in our office under medical supervision.
  • Observation: You’ll relax in a private, comfortable space for about 2 hours while our clinical team monitors you for safety and side effects.
  • After Treatment: Because Spravato® can cause temporary drowsiness or dizziness, you’ll need a responsible adult to drive you home after each session. Most patients can resume normal activities the next day.

Common Side Effects

Most side effects are temporary and mild. They can include:

  • Feeling sleepy or “spaced out”
  • Dizziness or lightheadedness
  • Nausea
  • Temporary increase in blood pressure

Our trained staff will monitor your comfort and safety throughout your visit.


Your Treatment Schedule

Spravato® therapy occurs in two phases:

  1. Induction Phase (Weeks 1–4): Twice-weekly treatments
  2. Maintenance Phase (Weeks 5+): Once-weekly or every other week, depending on your progress

Your provider will personalize your schedule to your needs.


Who Can Benefit from Spravato®

Spravato® may be a good fit for adults who:

  • Have not found relief from at least two antidepressant medications, or
  • Are experiencing depressive symptoms with suicidal thoughts despite treatment

A full evaluation with one of our clinicians will help determine if Spravato® is right for you.


Safety and Monitoring

Spravato® must be taken in a certified treatment center because of its short-term effects.

Our clinic provides:

  • Continuous monitoring during and after treatment
  • A calm, supportive environment
  • Coordination with your existing mental health providers

Your safety, comfort, and privacy are our top priorities.


Take the Next Step

If you or someone you care about is struggling with depression that hasn’t improved with standard treatment, Spravato® may offer a new path forward.

  • Call our office to schedule a consultation
  • Ask our team about our Spravato® treatment program

We’re here to support you on your journey toward healing and hope.



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